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Madras et al (2006) in a new paper demonstrated in vivo binding of modafinil to striatal DAT and thalamic Web in rhesus monkeys working with PET imaging. The investigators in contrast binding in the DAT probe [11C]CFT plus the Web probe [11C]MeNER in the absence of modafinil Together with the binding of these probes in the presence of modafinil to